Description

Vapreotide Acetate is a synthetic octapeptide analog of somatostatin, chemically modified for enhanced metabolic stability and receptor binding affinity. This compound is a critical active pharmaceutical ingredient (API) valued for its potent inhibitory effects on the secretion of growth hormone and various gastrointestinal hormones. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of therapeutic agents. The product is supplied under stringent quality control to ensure consistency and reliability for advanced pharmaceutical applications.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for therapeutic applications.
• Endocrine Disorder Treatment: Key component in drugs targeting acromegaly and symptoms of carcinoid syndrome (e.g., flushing, diarrhea).
• Gastroenteropancreatic Tumor Therapy: Used in medications for managing neuroendocrine tumors (NETs).
• Research & Development: Serves as a reference standard and a crucial compound in preclinical studies for novel somatostatin analogs.
• Peptide Chemistry Studies: Valuable for academic and industrial research in peptide synthesis, modification, and structure-activity relationships (SAR).

Basic Information

Product Name	Vapreotide Acetate
CAS No.	849479-74-9
Molecular Formula	C57H71N11O10S2 • xC2H4O2
Molecular Weight	~1131.3 g/mol (free base)
Synonyms	RC-160; BIM-23014; Vapreotide; [D-β-Nal1,Cys2,Tyr3,D-Trp4,Lys5,Cys6,Val-NH27]Somatostatin-14; Octapeptide RC 160; Sanvar; (3-(2-Naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valinyl-L-cysteinyl-L-threoninamide, cyclic (2→7)-disulfide, acetate)
EINECS	Contact for details

Quality Control

Our Vapreotide Acetate is manufactured and tested to meet exacting standards suitable for pharmaceutical development. Quality assurance protocols align with ICH guidelines and current industry best practices. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Certificates are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature between 15°C and 25°C (59°F and 77°F) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Acetate Content (Titration)	3.0 - 8.0%
Bacterial Endotoxins	< 10.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.