Description

2-Chloro-7-Fluoroquinazoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, enabling critical molecular modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of tyrosine kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in developing novel herbicides and pesticides by acting as a core scaffold for bioactive molecules.
• Material Science: Serves as a building block for creating specialized organic ligands and functionalized polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinazoline moiety into complex structures.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and corporate laboratories.

Basic Information

Product Name	2-Chloro-7-Fluoroquinazoline
CAS No.	956101-10-3
Molecular Formula	C8H3ClFN2
Molecular Weight	182.57 g/mol
Synonyms	2-Chloro-7-fluoroquinazoline; 7-Fluoro-2-chloroquinazoline; Quinazoline, 2-chloro-7-fluoro-; 2-Chloro-7-fluoro-quinazoline; 956101-10-3
EINECS	Contact for details

Quality Control

Our 2-Chloro-7-Fluoroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.