Description

8-Bromo-2-Chloroquinazoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its dual halogenated structure, which provides distinct, reactive sites for selective functionalization, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, where it serves as a key precursor for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the quinazoline scaffold.
• Material Science: Serves as a building block for creating organic semiconductors, liquid crystals, and advanced polymers with tailored electronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex substituents.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and methodological studies in heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-2-Chloroquinazoline
CAS No.	956100-63-3
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	2-Chloro-8-bromoquinazoline; 8-Bromo-2-chloro-quinazoline; Quinazoline, 8-bromo-2-chloro-; 956100-63-3; 8-Br-2-Cl-quinazoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-Chloroquinazoline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.