Description

8-Quinolinamine, 5-(4-Methyl-1-Piperazinyl)- is a high-purity, functionalized quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmacophore and building block for the research and development of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of potential drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Used in the design and synthesis of small molecule inhibitors for protein kinases, a major target class in cancer therapy.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study biological processes and identify new drug targets.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the functionalized quinoline-piperazine moiety into larger molecular architectures.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Material Science: Investigated as a precursor for functional organic materials, such as ligands for metal-organic frameworks (MOFs) or catalysts.

Basic Information

Item	Details
Product Name	8-Quinolinamine, 5-(4-Methyl-1-Piperazinyl)-
CAS No.	955413-27-1
Molecular Formula	C14H18N4
Molecular Weight	242.32 g/mol
Synonyms	5-(4-Methylpiperazin-1-yl)quinolin-8-amine; 8-Amino-5-(4-methyl-1-piperazinyl)quinoline; N-(5-(4-Methylpiperazin-1-yl)quinolin-8-yl)amine; 5-(4-Methylpiperazino)-8-aminoquinoline; 8-Amino-5-(N-methylpiperazino)quinoline; Quinolin-8-amine, 5-(4-methyl-1-piperazinyl)-; A potential intermediate for kinase inhibitor development.
EINECS	Contact for details

Quality Control

Our production of 8-Quinolinamine, 5-(4-Methyl-1-Piperazinyl)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for research applications. Identity and purity are confirmed via advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.