Description

4-Amino-8-Chloroquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, functionalized quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both amino and ester functionalities on the quinoline core, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of novel quinoline-based drug candidates, particularly for applications in antimicrobial and anticancer therapies.
• Agrochemical Synthesis: Used in the synthesis of advanced crop protection agents and pesticides, leveraging its heterocyclic structure for biological activity.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as a core structure for synthesizing advanced colorants and fluorescent markers due to the quinoline chromophore.
• Academic & R&D Laboratories: Employed as a standard reagent in methodological studies for heterocyclic chemistry, amination, and esterification reactions.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-Amino-8-Chloroquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	955328-43-5
Molecular Formula	C₁₂H₁₁ClN₂O₂
Molecular Weight	250.68 g/mol
Synonyms	Ethyl 4-Amino-8-chloroquinoline-3-carboxylate; 8-Chloro-4-aminoquinoline-3-carboxylic Acid Ethyl Ester; 4-Amino-8-chloro-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 4-amino-8-chloro-, ethyl ester; Ethyl 4-amino-8-chloro-3-quinolincarboxylate; 955328-43-5; 4-Amino-8-chloroquinoline-3-ethyl carboxylate
EINECS	Contact for details

Quality Control

Our 4-Amino-8-Chloroquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.