Description

6-(2,8-Bis-Trifluoromethyl-Quinolin-4-Ylmethyl)-Pyridin-3-Ol is a high-value, fluorinated heterocyclic compound that serves as a critical building block in advanced chemical synthesis. This compound matters for its unique structural features, combining a quinoline core with trifluoromethyl groups and a hydroxypyridine moiety, which are highly sought after for modulating the physicochemical properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, particularly where enhanced bioavailability, metabolic stability, and lipophilicity are required.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Precursor: Serves as a building block for specialty chemicals, including ligands for catalysis and monomers for advanced polymers.
• Fluorine Chemistry Research: An important compound for academic and industrial research focused on incorporating trifluoromethyl groups into complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise fluorinated structure.

Basic Information

Product Name	6-(2,8-Bis-Trifluoromethyl-Quinolin-4-Ylmethyl)-Pyridin-3-Ol
CAS No.	955315-33-0
Molecular Formula	C₁₈H₁₀F₆N₂O
Molecular Weight	384.28 g/mol
Synonyms	4-((6-Hydroxypyridin-3-yl)methyl)-2,8-bis(trifluoromethyl)quinoline; 2,8-Bis(trifluoromethyl)-4-((6-oxo-1,6-dihydropyridin-3-yl)methyl)quinoline; 955315-33-0; 6-(2,8-Bis(trifluoromethyl)quinolin-4-ylmethyl)pyridin-3-ol; 3-Pyridinol, 6-[(2,8-bis(trifluoromethyl)-4-quinolinyl)methyl]-
EINECS	Contact for details

Quality Control

Our 6-(2,8-Bis-Trifluoromethyl-Quinolin-4-Ylmethyl)-Pyridin-3-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) are available for every batch, detailing all relevant specifications to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.