Description

1-(2,4-Difluorophenyl)-2-Methoxyethan-1-Amine CAS NO 954584-30-6 is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity intermediate to enable efficient, scalable routes to complex target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Agrochemical Research: Used in the development of new-generation fluorinated pesticides and herbicides, where the difluorophenyl moiety enhances biological activity and metabolic stability.
• Ligand Synthesis: Serves as a building block for creating sophisticated chiral ligands and catalysts used in asymmetric synthesis.
• Material Science: Potential monomer or modifier in the synthesis of specialty polymers and advanced materials with unique properties.
• Fluorine Chemistry: A valuable substrate for studying structure-activity relationships (SAR) and introducing fluorine atoms into complex molecular architectures.

Basic Information

Item	Details
Product Name	1-(2,4-Difluorophenyl)-2-Methoxyethan-1-Amine
CAS No.	954584-30-6
Molecular Formula	C9H11F2NO
Molecular Weight	187.19 g/mol
Synonyms	1-(2,4-Difluorophenyl)-2-methoxyethanamine; 2-Methoxy-1-(2,4-difluorophenyl)ethanamine; (2,4-Difluorophenyl)(2-methoxyethyl)amine; 2,4-Difluoro-α-(methoxymethyl)benzylamine; 1-Amino-2-methoxy-1-(2,4-difluorophenyl)ethane; α-(Methoxymethyl)-2,4-difluorobenzylamine
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorophenyl)-2-Methoxyethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong alkalis and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Typical)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.