Description

6-Bromo-8-Methyl-1,2,3,4-Tetrahydroquinoline is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for the synthesis of complex molecules, offering a functionalized quinoline scaffold for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce bromine and methyl-substituted tetrahydroquinoline motifs into target structures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Employed in the research and development of organic electronic materials, such as charge-transport layers or light-emitting components, due to its electron-rich aromatic system.
• Ligand Synthesis: Acts as a starting material for creating novel nitrogen-containing ligands used in catalysis and coordination chemistry.
• Dye & Pigment Industry: Functions as an intermediate for synthesizing specialized quinoline-based dyes and colorants.
• Academic & Contract Research: Essential for methodological studies and library synthesis in academic laboratories and contract research organizations (CROs).

Basic Information

Product Name	6-Bromo-8-Methyl-1,2,3,4-Tetrahydroquinoline
CAS No.	954563-85-0
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	6-Bromo-8-methyl-1,2,3,4-tetrahydroquinoline; 8-Methyl-6-bromo-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-6-bromo-8-methylquinoline; Quinoline, 6-bromo-1,2,3,4-tetrahydro-8-methyl-; 6-Bromo-8-methyl-1,2,3,4-tetrahydro-quinoline; 6-Bromo-8-methyl-3,4-dihydro-1H-quinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Methyl-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.