Description

5-Chloro-8-Fluoro-1,2,3,4-Tetrahydroquinoline is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its fused quinoline structure, which serves as a privileged scaffold for developing novel bioactive molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Research: Used as a building block for developing new generations of herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	5-Chloro-8-Fluoro-1,2,3,4-Tetrahydroquinoline
CAS No.	954270-78-1
Molecular Formula	C9H7ClFN
Molecular Weight	183.61 g/mol
Synonyms	5-Chloro-8-fluoro-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-5-chloro-8-fluoroquinoline; 8-Fluoro-5-chloro-1,2,3,4-tetrahydroquinoline; 5-Chloro-8-fluoro-3,4-dihydro-2H-quinoline; Quinoline, 5-chloro-8-fluoro-1,2,3,4-tetrahydro-
EINECS	Contact for details

Quality Control

Our 5-Chloro-8-Fluoro-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.