Description

8-Fluoro-6-Methyl-1,2,3,4-Tetrahydroquinoline is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which is designed to modulate the physicochemical and biological properties of target compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the fluorine atom can enhance bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic molecules used in electronic materials or liquid crystals.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring a fluorinated tetrahydroquinoline core.
• Academic & Institutional Research: Used in universities and research institutes for methodological development and exploring new chemical spaces.

Basic Information

Product Name	8-Fluoro-6-Methyl-1,2,3,4-Tetrahydroquinoline
CAS No.	954260-80-1
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	6-Methyl-8-fluoro-1,2,3,4-tetrahydroquinoline; 8-Fluoro-6-methyl-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-8-fluoro-6-methylquinoline; 8-Fluoro-6-methyl-3,4-dihydro-1H-quinoline; Fluorinated Tetrahydroquinoline Derivative; F-Methyl-THQ; 954260-80-1 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 8-Fluoro-6-Methyl-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Purity (GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.