Description

tert-Butyl 2,8-diazaspiro[5.5]undecane-2-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a constrained spirocyclic diamine scaffold. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: The spirocyclic diamine structure is applicable in the design of inhibitors for proteases and other enzymatic targets.
• Ligand Synthesis for Catalysis: Can be utilized to develop novel chiral ligands for asymmetric synthesis and catalysis.
• Chemical Biology Probes: Employed in the creation of molecular probes to study biological processes and protein function.

Basic Information

Product Name	tert-Butyl 2,8-diazaspiro[5.5]undecane-2-carboxylate
CAS No.	954240-14-3
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	2,8-Diazaspiro[5.5]undecane-2-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 2,8-diazaspiro[5.5]undecane-2-carboxylate; 2-(tert-Butoxycarbonyl)-2,8-diazaspiro[5.5]undecane; Boc-2,8-diazaspiro[5.5]undecane; 954240-14-3; Spirocyclic Diamine Boc Derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,8-diazaspiro[5.5]undecane-2-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.