Description

4-Chloro-6-Methoxy-2-Thiophen-2-Ylquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline-thiophene hybrid structure. This compound matters as a critical building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical development, and materials science for creating new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug molecules targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Agrochemical Development: Acts as a building block for novel pesticides and herbicides due to its heterocyclic framework.
• Material Science: Investigated for use in organic electronic materials, such as OLEDs or semiconductors, leveraging its conjugated system.
• Chemical Biology: Utilized as a molecular probe or tag in biochemical research and assay development.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.

Basic Information

Product Name	4-Chloro-6-Methoxy-2-Thiophen-2-Ylquinoline
CAS No.	954225-75-3
Molecular Formula	C₁₄H₁₀ClNOS
Molecular Weight	275.75 g/mol
Synonyms	4-Chloro-6-methoxy-2-(thiophen-2-yl)quinoline; 2-(2-Thienyl)-4-chloro-6-methoxyquinoline; Quinoline, 4-chloro-6-methoxy-2-(2-thienyl)-; 954225-75-3; 4-Chloro-6-methoxy-2-(2-thienyl)quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Methoxy-2-Thiophen-2-Ylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.