Description

3-(4-Chloro-2-Methyl-Phenoxy)-Piperidine is a versatile and high-value piperidine derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for research and development in the pharmaceutical and agrochemical sectors, where its unique phenoxy-piperidine scaffold enables the creation of novel active molecules. It is primarily sought by R&D chemists, process development scientists, and manufacturers developing new active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) targeting drugs, receptor modulators, and other bioactive molecules.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated phenoxy moiety.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its piperidine core.
• Ligand and Catalyst Development: Serves as a precursor or framework for creating specialized ligands in catalytic systems and molecular recognition.
• Academic and Industrial R&D: A valuable reagent for universities and corporate R&D labs exploring new chemical entities and synthetic pathways.

Basic Information

Product Name	3-(4-Chloro-2-Methyl-Phenoxy)-Piperidine
CAS No.	954223-28-0
Molecular Formula	C12H16ClNO
Molecular Weight	225.72 g/mol
Synonyms	3-[(4-Chloro-2-methyl)phenoxy]piperidine; 3-(4-Chloro-o-tolyloxy)piperidine; Piperidine, 3-[(4-chloro-2-methyl)phenoxy]-; 954223-28-0; 4-Chloro-2-methylphenoxy piperidine-3; 3-(4-Chloro-2-methylphenoxy)piperidine
EINECS	Contact for details

Quality Control

Our 3-(4-Chloro-2-Methyl-Phenoxy)-Piperidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediates and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.