Description

2-Chloro-1,1-Bis(4-Chlorophenyl)-2,2-Difluoro-Ethanol is a specialized organofluorine and organochlorine compound that serves as a critical synthetic intermediate. Its unique structure, featuring multiple halogen substituents, makes it a valuable building block for creating complex molecules with specific electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis projects.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing anti-infective properties.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the difluoro and dichloro motifs can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal, chemical, or optical resistance.
• Ligand and Catalyst Development: Employed in organic chemistry research to create novel chiral ligands or organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research into the effects of fluorine substitution on molecular reactivity and physicochemical properties.

Basic Information

Product Name	2-Chloro-1,1-Bis(4-Chlorophenyl)-2,2-Difluoro-Ethanol
CAS No.	1428-03-1
Molecular Formula	C14H9Cl3F2O
Molecular Weight	337.57 g/mol
Synonyms	2-Chloro-1,1-bis(4-chlorophenyl)-2,2-difluoroethanol; 1,1-Bis(4-chlorophenyl)-2-chloro-2,2-difluoroethanol; α-Chloro-α,α-difluoro-4,4'-dichlorobenzhydrol; 2,2-Difluoro-2-chloro-1,1-bis(4-chlorophenyl)ethanol; (4,4'-Dichlorophenyl)difluorochloromethylcarbinol
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-1,1-Bis(4-Chlorophenyl)-2,2-Difluoro-Ethanol is produced and analyzed under strict quality management protocols. We ensure identity, purity, and consistency through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. Our quality system supports cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.