Description

Diethyl 4-Chloroquinoline-3,6-Dicarboxylate is a high-purity, versatile organic intermediate of significant importance in advanced chemical synthesis. Its value lies in its functionalized quinoline core, which serves as a critical building block for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinoline-based drug candidates, including potential antimalarial, anticancer, and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the chloroquinoline scaffold.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing specialized quinoline dyes and colorants with specific light-absorption properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.
• Custom Synthesis: A starting material for the contract manufacturing of complex, customer-specific molecules requiring a functionalized quinoline structure.

Basic Information

Product Name	Diethyl 4-Chloroquinoline-3,6-Dicarboxylate
CAS No.	954218-44-1
Molecular Formula	C15H14ClNO4
Molecular Weight	307.73 g/mol
Synonyms	4-Chloroquinoline-3,6-dicarboxylic acid diethyl ester; Diethyl 4-chloro-3,6-quinolinedicarboxylate; 3,6-Quinolinedicarboxylic acid, 4-chloro-, diethyl ester; 4-Chloro-3,6-quinolinedicarboxylic Acid Diethyl Ester; Ethyl 4-chloroquinoline-3,6-dicarboxylate; Diethyl 4-chloroquinoline-3,6-dicarboxylate; CAS 954218-44-1
EINECS	Contact for details

Quality Control

Our Diethyl 4-Chloroquinoline-3,6-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound should be kept away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.