Description

Ethyl6-Bromo-4-Chloro-7-Fluoroquinoline-3-Carboxylate is a high-purity, multi-halogenated quinoline derivative serving as a critical advanced pharmaceutical intermediate. Its complex halogenated structure makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of potent antibacterial and antiviral agents. This compound is essential for research institutions and pharmaceutical manufacturers focused on next-generation quinolone-based therapeutics and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel fluoroquinolone antibiotic candidates targeting resistant bacterial strains.
• Agrochemical Research: Used in developing advanced fungicides and bactericides with enhanced activity and environmental profiles.
• Chemical Synthesis: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• API Development: Integral building block for the commercial-scale production of complex active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and process development.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new heterocyclic compounds with potential biological activity.

Basic Information

Product Name	Ethyl6-Bromo-4-Chloro-7-Fluoroquinoline-3-Carboxylate
CAS No.	953803-84-4
Molecular Formula	C₁₂H₈BrClFNO₂
Molecular Weight	332.55 g/mol
Synonyms	Ethyl 6-Bromo-4-chloro-7-fluoroquinoline-3-carboxylate; 6-Bromo-4-chloro-7-fluoroquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 6-bromo-4-chloro-7-fluoro-, ethyl ester; Ethyl 6-bromo-4-chloro-7-fluoro-3-quinolinecarboxylate; 953803-84-4; BCFQ Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl6-Bromo-4-Chloro-7-Fluoroquinoline-3-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.