Description

2-Chloro-6-Bromo-7-Methoxyquinazoline CAS NO 953040-63-6 is a high-purity, multi-functional quinazoline derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it an indispensable intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other small-molecule drug candidates targeting cancer and inflammatory diseases.
• Agrochemical Research: Used as a core scaffold for developing new herbicides and fungicides with specific modes of action.
• Chemical Biology: Employed in the design and synthesis of chemical probes for studying enzyme function and signal transduction pathways.
• Material Science: Serves as a starting material for creating functionalized organic compounds with potential applications in organic electronics.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	2-Chloro-6-Bromo-7-Methoxyquinazoline
CAS No.	953040-63-6
Molecular Formula	C9H6BrClN2O
Molecular Weight	273.51 g/mol
Synonyms	2-Chloro-6-bromo-7-methoxyquinazoline; 7-Methoxy-2-chloro-6-bromoquinazoline; Quinazoline, 2-chloro-6-bromo-7-methoxy-; 953040-63-6; 2-Chloro-6-bromo-7-methoxy-quinazoline; 6-Bromo-2-chloro-7-methoxyquinazoline
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Bromo-7-Methoxyquinazoline is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supported by a detailed Certificate of Analysis (COA) that includes results from HPLC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.