Description

Benzaldehyde, 2-Amino-3-Methoxy-6-(Trifluoromethyl)- is a specialized trifluoromethyl-substituted benzaldehyde derivative, serving as a high-value synthetic intermediate. This compound matters for its unique molecular architecture, combining an amino group, a methoxy substituent, and a trifluoromethyl group on a benzaldehyde core, which is critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where the introduction of fluorine atoms is desired to enhance metabolic stability, lipophilicity, or binding affinity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials.
• Fluorine Chemistry: An essential substrate for studying structure-activity relationships (SAR) in medicinal and agrochemical chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.
• Academic & Industrial R&D: Utilized in laboratories for methodological development and exploratory synthesis of complex heterocycles.

Basic Information

Product Name	Benzaldehyde, 2-Amino-3-Methoxy-6-(Trifluoromethyl)-
CAS No.	953040-19-2
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	2-Amino-3-methoxy-6-(trifluoromethyl)benzaldehyde; 6-(Trifluoromethyl)-2-amino-3-methoxybenzaldehyde; 2-Amino-α,α,α-trifluoro-3-methoxy-o-tolualdehyde; 3-Methoxy-2-amino-6-trifluoromethylbenzaldehyde; 2-Amino-3-methoxy-α,α,α-trifluoro-p-tolualdehyde; 6-Trifluoromethyl-2-amino-3-methoxybenzaldehyde; o-Amino-m-methoxy-α,α,α-trifluorotoluic aldehyde
EINECS	Contact for details

Quality Control

Our Benzaldehyde, 2-Amino-3-Methoxy-6-(Trifluoromethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP (current Good Manufacturing Practice) standards for advanced intermediates ensures reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.