Description

8-Quinazolinol, 7-Bromo-2,5-Dichloro- is a high-purity, multi-halogenated quinazoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile chemical building block for the development of novel active molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce complex halogenated quinazoline scaffolds into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active molecules containing the quinazoline core.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the halogenated quinazoline structure may confer specific biological activity.
• Material Science: Serves as a building block for creating advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic electronics.
• Chemical Biology Probe Development: Utilized in research to create molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: Employed in synthetic chemistry laboratories for method development and exploring new chemical reactions involving halogenated heterocycles.

Basic Information

Product Name	8-Quinazolinol, 7-Bromo-2,5-Dichloro-
CAS No.	953039-87-7
Molecular Formula	C8H3BrCl2N2O
Molecular Weight	294.93 g/mol
Synonyms	7-Bromo-2,5-dichloroquinazolin-8-ol; 7-Bromo-2,5-dichloro-8-hydroxyquinazoline; 2,5-Dichloro-7-bromo-8-quinazolinol; 8-Hydroxy-7-bromo-2,5-dichloroquinazoline; Quinazolin-8-ol, 7-bromo-2,5-dichloro-; 7-Bromo-2,5-dichloro-8(1H)-quinazolinone (tautomer); BDDQ (abbreviation); 953039-87-7 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 8-Quinazolinol, 7-Bromo-2,5-Dichloro- is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for advanced intermediates and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.