Description

7-Quinazolinecarboxylic Acid, 2-Chloro-, Methyl Ester is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for constructing complex heterocyclic frameworks, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinazoline-based drug candidates, including potential kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides that leverage the quinazoline scaffold for biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex molecules in custom synthesis and contract manufacturing projects.
• Academic & R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Material Science: Potential intermediate for the synthesis of organic electronic materials or specialty dyes and pigments.

Basic Information

Product Name	7-Quinazolinecarboxylic Acid, 2-Chloro-, Methyl Ester
CAS No.	953039-79-7
Molecular Formula	C11H9ClN2O2
Molecular Weight	236.65 g/mol
Synonyms	Methyl 2-chloro-7-quinazolinecarboxylate; 2-Chloro-7-quinazolinecarboxylic acid methyl ester; 2-Chloroquinazoline-7-carboxylic acid methyl ester; Quinazoline-7-carboxylic acid, 2-chloro-, methyl ester; Methyl 2-chloroquinazoline-7-carboxylate; 953039-79-7; 2-Chloro-7-methoxycarbonylquinazoline
EINECS	Contact for details

Quality Control

Our 7-Quinazolinecarboxylic Acid, 2-Chloro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards in research and cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.