Description

7-Bromo-2-Chloroquinazoline is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its dual halogenated structure, which provides distinct reactive sites for selective functionalization and cross-coupling reactions. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinazoline core into more complex molecules.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and methodological studies in heterocyclic chemistry.

Basic Information

Product Name	7-Bromo-2-Chloroquinazoline
CAS No.	953039-66-2
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	2-Chloro-7-bromoquinazoline; 7-Bromo-2-chloro-quinazoline; Quinazoline, 7-bromo-2-chloro-; 953039-66-2; 7-Bromo-2-chloroquinazoline; 2-Chloro-7-bromo-quinazoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-2-Chloroquinazoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.