Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[(1,1-Dimethylethoxy)Carbonyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel fluoroquinolone antibiotics, enabling the development of next-generation therapeutics. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the global pharmaceutical and fine chemical industries focused on anti-infective drug discovery and production.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for fluoroquinolone-class antibiotics.
• Antibiotic Research & Development: Used in medicinal chemistry for the design, optimization, and scale-up of new antibacterial agents targeting resistant pathogens.
• Process Chemistry: Employed in route scouting and process optimization studies for the commercial manufacturing of complex drug molecules.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions in drug development pipelines.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing tailored chemical entities for clients.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) of quinolone derivatives.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[(1,1-Dimethylethoxy)Carbonyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-, Ethyl Ester
CAS No.	952653-63-3
Molecular Formula	C24H28FN3O5
Molecular Weight	457.50 g/mol
Synonyms	Ethyl 1-cyclopropyl-7-[4-[(tert-butoxy)carbonyl]piperazin-1-yl]-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1-Cyclopropyl-7-[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 1-Cyclopropyl-6-fluoro-7-(4-(N-tert-butoxycarbonyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester; BOC-Pip-ethyl Ester Intermediate; Fluoroquinolone Intermediate BOC-Protected; 952653-63-3; Ethyl 1-cyclopropyl-6-fluoro-7-(4-(tert-butoxycarbonyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[(1,1-Dimethylethoxy)Carbonyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-, Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent degradation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.