Description

trans-3-Hydroxycyclopentanecarbonitrile is a versatile chiral nitrile building block of significant interest in advanced organic synthesis. Its value lies in the functional group combination of a protected hydroxyl group and a nitrile, which serves as a precursor to carboxylic acids, amides, and other heterocycles. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry.
• Fine Chemical Production: Serves as a building block for fragrances, flavors, and other specialty chemicals where precise molecular structure is critical.
• Academic & Industrial Research: A valuable reagent in methodological chemistry research for studying cyclopentane-based transformations and asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of specialized polymers and liquid crystals with tailored properties.

Basic Information

Product Name	trans-3-Hydroxycyclopentanecarbonitrile
CAS No.	952616-17-0
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	(1R,3S)-3-Hydroxycyclopentanecarbonitrile; (1S,3R)-3-Hydroxycyclopentanecarbonitrile; trans-3-Hydroxycyclopentane-1-carbonitrile; 3-Hydroxycyclopentanecarbonitrile (trans-); Cyclopentanecarbonitrile, 3-hydroxy-, trans-; 952616-17-0; (1R,3S)-3-Hydroxy-cyclopentanecarbonitrile
EINECS	Contact for details

Quality Control

Our trans-3-Hydroxycyclopentanecarbonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.