Description

2-Chloro-4,6-dimethoxyquinoline is a high-purity, functionalized quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile halogenated and methoxylated scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for researchers and manufacturers in the fine chemical, pharmaceutical, and material science industries who require reliable, high-quality building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobials, and other bioactive heterocycles.
• Agrochemical Research: Used in the creation of new herbicides, fungicides, and plant growth regulators that leverage the quinoline core structure.
• Material Science Precursor: Serves as a monomer or functional unit in the development of organic semiconductors, luminescent materials, and advanced polymers.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce the quinoline moiety into more complex architectures.
• Dye and Pigment Manufacturing: Acts as a precursor for the synthesis of specialized quinoline-based dyes and colorants.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in university and corporate research laboratories.

Basic Information

Item	Details
Product Name	2-Chloro-4,6-Dimethoxyquinoline
CAS No.	952435-01-7
Molecular Formula	C₁₁H₁₀ClNO₂
Molecular Weight	223.66 g/mol
Synonyms	2-Chloro-4,6-dimethoxyquinoline; 4,6-Dimethoxy-2-chloroquinoline; Quinoline, 2-chloro-4,6-dimethoxy-; 952435-01-7; 2-Chloro-4,6-bis(methoxy)quinoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-4,6-dimethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.