Description

2-Chloro-4-Methyl-6-(Trifluoromethoxy)Quinoline is a high-value, multi-functional heterocyclic building block distinguished by its unique halogenated and trifluoromethoxy-substituted quinoline core. This compound is critical for advanced research and development, particularly in the synthesis of complex molecules where its specific substitution pattern imparts desirable electronic and steric properties. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, particularly for antiviral, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences industry.

Basic Information

Item	Details
Product Name	2-Chloro-4-Methyl-6-(Trifluoromethoxy)Quinoline
CAS No.	952434-91-2
Molecular Formula	C12H7ClF3NO
Molecular Weight	273.64 g/mol
Synonyms	6-(Trifluoromethoxy)-2-chloro-4-methylquinoline; 2-Chloro-4-methyl-6-(trifluoromethoxy)quinoline; 4-Methyl-2-chloro-6-trifluoromethoxyquinoline; Quinoline, 2-chloro-4-methyl-6-(trifluoromethoxy)-; 952434-91-2
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Methyl-6-(Trifluoromethoxy)Quinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (NMR, IR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.