Description

4-[4-(Trifluoromethyl)-2-Pyridinyl]Benzenecarbaldehyde is a high-purity aromatic aldehyde building block featuring a trifluoromethylpyridine moiety, offering unique electronic and steric properties for advanced synthesis. This compound is critical for medicinal chemistry and materials science research, where its structure enables the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, leveraging the stability imparted by the trifluoromethyl group.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Biology Probes: Useful for creating fluorescent tags or affinity probes due to its reactive aldehyde group for bioconjugation.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	4-[4-(Trifluoromethyl)-2-Pyridinyl]Benzenecarbaldehyde
CAS No.	952182-74-0
Molecular Formula	C13H8F3NO
Molecular Weight	251.21 g/mol
Synonyms	4-[4-(Trifluoromethyl)pyridin-2-yl]benzaldehyde; 2-(4-Formylphenyl)-4-(trifluoromethyl)pyridine; 4'-(4-Trifluoromethyl-2-pyridyl)benzaldehyde; 4-(4-Trifluoromethyl-2-pyridinyl)benzaldehyde; 4-(4-Trifluoromethylpyridin-2-yl)benzaldehyde; 4-Formylphenyl 4-trifluoromethyl-2-pyridyl ketone (precursor-related); p-(4-Trifluoromethyl-2-pyridyl)benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-[4-(Trifluoromethyl)-2-Pyridinyl]Benzenecarbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support development and commercial projects with material suitable for research use and can supply grades compliant with ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storage under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.