Description

Ethyl 2-(Trifluoromethyl)-Quinoline-7-Carboxylate is a high-value, fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound is prized for its unique molecular architecture, which combines a quinoline core with a trifluoromethyl group and an ester functionality, enabling precise modifications in target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, where the trifluoromethyl group can enhance biological activity, metabolic stability, and lipophilicity.
• Material Science Research: Serves as a specialized monomer or ligand precursor for creating advanced organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent probes or enzyme inhibitors for biochemical and diagnostic research applications.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Ethyl 2-(Trifluoromethyl)-Quinoline-7-Carboxylate
CAS No.	952182-55-7
Molecular Formula	C₁₃H₁₀F₃NO₂
Molecular Weight	269.22 g/mol
Synonyms	Ethyl 2-(trifluoromethyl)-7-quinolinecarboxylate; 7-Quinolinecarboxylic acid, 2-(trifluoromethyl)-, ethyl ester; Ethyl 2-trifluoromethylquinoline-7-carboxylate; 2-Trifluoromethyl-quinoline-7-carboxylic acid ethyl ester; Quinoline-7-carboxylic acid, 2-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Trifluoromethyl)-Quinoline-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.