Description

2-(Trifluoromethyl)Quinoline-6-Carboxylic Acid CAS NO 952182-51-3 is a high-value, fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid group and a trifluoromethyl substituent, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at research and development teams within the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas like kinase inhibitors, anti-infectives, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Fluorine Chemistry Building Block: Essential for medicinal and agrochemical chemists exploring structure-activity relationships (SAR) by introducing fluorine atoms.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Item	Detail
Product Name	2-(Trifluoromethyl)Quinoline-6-Carboxylic Acid
CAS No.	952182-51-3
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	6-Quinolinecarboxylic acid, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)-6-quinolinecarboxylic acid; 2-Trifluoromethylquinoline-6-carboxylic acid; Quinoline-6-carboxylic acid, 2-(trifluoromethyl)-; 952182-51-3; 2-TFMQA
EINECS	Contact for details

Quality Control

Every batch of 2-(Trifluoromethyl)Quinoline-6-Carboxylic Acid is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee the material meets your precise research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.