Description

Ethyl 2-(Trifluoromethyl)-Quinoline-6-Carboxylate is a high-value, fluorinated quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the unique combination of the quinoline scaffold and the electron-withdrawing trifluoromethyl group, enabling precise modulation of molecular properties in target compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to construct novel active ingredients with enhanced potency and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms contribute to improved bioactivity and environmental persistence.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and the effects of fluorine substitution on heterocyclic systems.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags or molecular probes for studying biological processes.

Basic Information

Product Name	Ethyl 2-(Trifluoromethyl)-Quinoline-6-Carboxylate
CAS No.	952182-49-9
Molecular Formula	C₁₃H₁₀F₃NO₂
Molecular Weight	269.22 g/mol
Synonyms	Ethyl 2-(trifluoromethyl)-6-quinolinecarboxylate; 6-Quinolinecarboxylic acid, 2-(trifluoromethyl)-, ethyl ester; Ethyl 2-trifluoromethylquinoline-6-carboxylate; 2-Trifluoromethylquinoline-6-carboxylic acid ethyl ester; Quinoline-6-carboxylic acid, 2-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Trifluoromethyl)-Quinoline-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.