Description

4-Amino-1-Boc-2-Methylpiperidine is a high-purity, protected piperidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a sterically defined, nitrogen-containing scaffold with orthogonal protecting groups, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and complex fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of piperidine-based drug candidates, including receptor modulators and enzyme inhibitors.
• Agrochemical Research: Used in constructing complex molecules for developing new pesticides and herbicides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics & Bioactive Molecules: Incorporated into the backbone of peptidomimetic compounds to modulate biological activity and stability.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for custom synthesis projects requiring high-fidelity chiral intermediates.
• Academic & R&D Laboratories: Utilized in methodological research and the discovery of new synthetic routes involving amine chemistry.

Basic Information

Product Name	4-Amino-1-Boc-2-Methylpiperidine
CAS No.	952182-04-6
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-Boc-4-Amino-2-Methylpiperidine; tert-Butyl 4-amino-2-methylpiperidine-1-carboxylate; 2-Methyl-4-aminopiperidine-1-carboxylic acid tert-butyl ester; 4-Amino-2-methyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-amino-2-methylpiperidine; 4-Amino-2-methylpiperidine-1-Boc; Boc-4-Amino-2-Methylpiperidine
EINECS	Contact for details

Quality Control

Our 4-Amino-1-Boc-2-Methylpiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.