Description

4-Chloro-2-Methyl-6-Trifluoromethoxyquinoline is a high-purity, multi-functional quinoline derivative of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and material science industries seeking to incorporate its unique trifluoromethoxy-substituted quinoline scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core and the metabolic stability imparted by the trifluoromethoxy group.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers, organic semiconductors, and liquid crystals due to its electron-deficient aromatic system.
• Chemical Synthesis: Employed in organic chemistry research for constructing complex heterocyclic systems and in metal-catalyzed cross-coupling reactions.
• Fluorescent Probe Development: The quinoline structure makes it a candidate scaffold for developing novel fluorescent dyes and sensors for biochemical assays.

Basic Information

Product Name	4-Chloro-2-Methyl-6-Trifluoromethoxyquinoline
CAS No.	951905-08-1
Molecular Formula	C12H7ClF3NO
Molecular Weight	273.64 g/mol
Synonyms	4-Chloro-2-methyl-6-(trifluoromethoxy)quinoline; 6-(Trifluoromethoxy)-4-chloro-2-methylquinoline; 2-Methyl-4-chloro-6-trifluoromethoxyquinoline; Quinoline, 4-chloro-2-methyl-6-(trifluoromethoxy)-; 951905-08-1; 4-Chloro-2-methyl-6-trifluoromethoxy-quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-6-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.