Description

n-Benzyl-2-Bromo-5-(Trifluoromethoxy)Benzenesulfonamide CAS NO 951885-49-7 is a high-purity, specialized sulfonamide derivative designed for advanced chemical synthesis and pharmaceutical research. This compound serves as a critical building block for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, offering unique reactivity from its bromo and trifluoromethoxy substituents. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for lead optimization and the creation of new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel sulfonamide-based drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the sulfonamide core.
• Chemical Synthesis Building Block: The reactive bromine atom enables further functionalization via cross-coupling reactions (e.g., Suzuki, Heck) for creating complex molecular architectures.
• Material Science: Potential monomer or additive for developing specialty polymers with specific electronic or surface properties.
• Biochemical Probe Development: Used in medicinal chemistry to study enzyme inhibition and structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and scale-up projects.

Basic Information

Product Name	n-Benzyl-2-Bromo-5-(Trifluoromethoxy)Benzenesulfonamide
CAS No.	951885-49-7
Molecular Formula	C14H11BrF3NO3S
Molecular Weight	410.21 g/mol
Synonyms	2-Bromo-5-(trifluoromethoxy)-N-(phenylmethyl)benzenesulfonamide; N-Benzyl-2-bromo-α,α,α-trifluoro-p-anisolsulfonamide; Benzenesulfonamide, N-(phenylmethyl)-2-bromo-5-(trifluoromethoxy)-; BBTBS; Bn-2-Br-5-TFM-BSA
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for all critical parameters are available upon request. We adhere to strict internal quality protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.