Description

1-(3-Bromo-5-Trifluoromethylphenylsulfonyl)Pyrrolidine is a high-purity, advanced pharmaceutical intermediate and building block characterized by its unique sulfonamide and halogenated aromatic structure. This compound is valued for its role in facilitating complex molecular transformations, particularly in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl and bromo substituents contribute to bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized polymers and advanced materials requiring specific sulfonamide linkages.
• Chemical Biology & Proteomics: Employed as a specialty reagent for designing enzyme inhibitors or activity-based probes due to its electrophilic sulfonyl group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	1-(3-Bromo-5-Trifluoromethylphenylsulfonyl)Pyrrolidine
CAS No.	951884-59-6
Molecular Formula	C11H10BrF3NO2S
Molecular Weight	358.17 g/mol
Synonyms	1-[(3-Bromo-5-(trifluoromethyl)phenyl)sulfonyl]pyrrolidine; Pyrrolidine, 1-[(3-bromo-5-(trifluoromethyl)phenyl)sulfonyl]-; 3-Bromo-5-trifluoromethylbenzenesulfonylpyrrolidine; N-((3-Bromo-5-(trifluoromethyl)phenyl)sulfonyl)pyrrolidine; 951884-59-6; 1-(3-Bromo-5-trifluoromethylbenzenesulfonyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-5-Trifluoromethylphenylsulfonyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.