Description

5-(4-Bromophenyl)Picolinonitrile is a high-purity organic building block featuring a bromophenyl group and a picolinonitrile moiety. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive scaffold.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target identification and validation.
• Cross-Coupling Reactions: The bromophenyl group makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Utilized for the preparation of novel nitrogen-containing ligands for catalysis and coordination chemistry.

Basic Information

Product Name	5-(4-Bromophenyl)Picolinonitrile
CAS No.	951657-98-0
Molecular Formula	C₁₂H₇BrN₂
Molecular Weight	259.10 g/mol
Synonyms	5-(4-Bromophenyl)-2-cyanopyridine; 2-Cyano-5-(4-bromophenyl)pyridine; 4-Bromo-5-(pyridin-2-yl)benzonitrile; 5-(p-Bromophenyl)picolinonitrile; 2-Pyridinecarbonitrile, 5-(4-bromophenyl)-; 951657-98-0; 5-(4-Bromophenyl)-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-(4-Bromophenyl)Picolinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications in GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.