Description

3-(Trifluoromethyl)Cyclohexanamine Hcl is a high-purity, fluorinated amine hydrochloride salt with the CAS number 951627-67-1. This compound is a valuable chiral building block and intermediate, prized for its ability to introduce the trifluoromethyl group and a basic amine functionality into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its unique physicochemical properties can enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials requiring fluorinated amine components.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	3-(Trifluoromethyl)Cyclohexanamine Hcl
CAS No.	951627-67-1
Molecular Formula	C7H13ClF3N
Molecular Weight	203.63 g/mol
Synonyms	3-(Trifluoromethyl)cyclohexanamine hydrochloride; 3-(Trifluoromethyl)cyclohexylamine HCl; 3-(Trifluoromethyl)cyclohexan-1-amine hydrochloride; 3-(Trifluoromethyl)-1-cyclohexanamine hydrochloride; Cyclohexanamine, 3-(trifluoromethyl)-, hydrochloride (1:1); 951627-67-1; (3-(Trifluoromethyl)cyclohexyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-(Trifluoromethyl)Cyclohexanamine Hcl is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. Our quality assurance includes identity confirmation, purity analysis, and impurity profiling. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting specifications for assay, enantiomeric excess (where applicable), and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.