Description

Ethyl 1,4-Dihydro-6-Iodo-8-Methyl-4-Oxoquinoline-3-Carboxylate is a high-purity, iodinated quinoline derivative serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of antimicrobial and anticancer agents. Pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) need this high-value building block to accelerate their drug discovery and process development pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new quinolone-based antibiotic candidates.
• Antimicrobial Agent Research: Used in structure-activity relationship (SAR) studies to develop compounds with enhanced efficacy against resistant bacterial strains.
• Oncology Drug Discovery: Serves as a scaffold for synthesizing potential anticancer agents targeting specific cellular pathways.
• Chemical Synthesis Building Block: Utilized in organic synthesis for the introduction of the iodinated quinoline moiety into more complex molecular architectures.
• Process Chemistry & Scale-Up: Employed in the optimization and pilot-scale production of target molecules for clinical trials.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Ethyl 1,4-Dihydro-6-Iodo-8-Methyl-4-Oxoquinoline-3-Carboxylate
CAS No.	951006-39-6
Molecular Formula	C₁₃H₁₂INO₃
Molecular Weight	357.15 g/mol
Synonyms	6-Iodo-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester; Ethyl 6-iodo-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1,4-Dihydro-6-iodo-8-methyl-4-oxoquinoline-3-carboxylic Acid Ethyl Ester; 951006-39-6; 6-Iodo-8-methyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; Ethyl 6-iodo-8-methyl-1,4-dihydro-4-oxo-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 1,4-dihydro-6-iodo-8-methyl-4-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 1,4-Dihydro-6-Iodo-8-Methyl-4-Oxoquinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.