Description

Diethyl 2-((4-Iodo-2-Methylphenylamino)Methylene)Malonate is a specialized malonate derivative featuring an iodinated aniline moiety, serving as a critical synthetic intermediate in advanced organic synthesis. Its molecular architecture, combining a reactive methylene malonate ester with a halogenated aromatic amine, makes it a versatile building block for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting specific receptors or enzymes.
• Agrochemical Research: Building block for developing new herbicides, fungicides, or plant growth regulators with novel modes of action.
• Organic Synthesis: Versatile reagent for constructing complex heterocycles like quinolines, acridines, or other nitrogen-containing fused ring systems.
• Material Science: Intermediate in the creation of organic semiconductors, dyes, or photoactive materials leveraging its conjugated system.
• Chemical Biology Probes: Used to develop molecular probes or tags due to the reactivity of the malonate group and the presence of the iodine atom for further functionalization.

Basic Information

Product Name	Diethyl 2-((4-Iodo-2-Methylphenylamino)Methylene)Malonate
CAS No.	951006-38-5
Molecular Formula	C15H18INO4
Molecular Weight	403.21 g/mol
Synonyms	Diethyl (2Z)-2-[(4-iodo-2-methylphenyl)imino]malonate; Diethyl 2-[(4-Iodo-2-methylphenyl)imino]malonate; 2-((4-Iodo-2-methylphenylamino)methylene)malonic acid diethyl ester; Propanedioic acid, 2-[(4-iodo-2-methylphenyl)imino]-, 1,3-diethyl ester; (Z)-Diethyl 2-((4-iodo-2-methylphenyl)imino)malonate; Diethyl (Z)-2-((4-iodo-o-tolyl)imino)malonate
EINECS	Contact for details

Quality Control

Our Diethyl 2-((4-Iodo-2-Methylphenylamino)Methylene)Malonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC, GC, and NMR, are validated to provide reliable specifications for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature (store away from light), the container should be opaque or stored in dark conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.