Description

1-Thia-4-Azaspiro[4.4]Nonan-6-One is a sophisticated spirocyclic heterocyclic compound featuring a unique fused ring system containing both sulfur and nitrogen atoms. This complex molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate and a key building block in modern organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the construction of novel active molecules. The compound is supplied to meet the stringent purity requirements of process chemistry and medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting the central nervous system, infectious diseases, and metabolic disorders.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new bioactive chemical space.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides with unique modes of action.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex spirocyclic and heterocyclic frameworks.
• Chemical Biology Probe: Utilized in the development of molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	1-Thia-4-Azaspiro[4.4]Nonan-6-One
CAS No.	950840-29-6
Molecular Formula	C7H11NOS
Molecular Weight	157.23 g/mol
Synonyms	1-Thia-4-azaspiro[4.4]nonan-6-one; 6-Thia-9-azaspiro[4.4]nonan-8-one; Spiro[thiazolidine-4,1'-cyclopentane]-2-one; 1'-Thia-4'-azaspiro[cyclopentane-1,4'-thiazolidin]-2'-one; 950840-29-6; 1-Thia-4-azaspiro(4.4)nonan-6-one
EINECS	Contact for details

Quality Control

Our production of 1-Thia-4-Azaspiro[4.4]Nonan-6-One adheres to a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for advanced intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.