Description

2H-[2,7]Naphthyridin-1-One Hydrobromide is a high-purity organic salt compound, primarily valued as a critical pharmaceutical intermediate and building block in advanced organic synthesis. Its naphthyridine core structure makes it a versatile scaffold for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Organic Synthesis Reagent: Used as a versatile precursor for constructing complex heterocyclic compounds in medicinal chemistry and material science research.
• Agrochemical Research: Serves as a core structure for developing new pesticides and herbicides with specific biological activity.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and coordination chemistry applications.
• Academic and R&D: Employed in university and corporate research laboratories for method development and exploring new chemical entities.
• Fine Chemical Production: Integrated into multi-step synthesis processes for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	2H-[2,7]Naphthyridin-1-One Hydrobromide
CAS No.	950746-19-7
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	1(2H)-Naphthyridinone, hydrobromide; 2H-[2,7]Naphthyridin-1-one HBr; 1-Hydroxy-2,7-naphthyridine hydrobromide; 2,7-Naphthyridin-1(2H)-one hydrobromide; 1-Oxo-1,2-dihydro-2,7-naphthyridine hydrobromide; 950746-19-7; 2,7-Naphthyridinone hydrobromide
EINECS	Contact for details

Quality Control

Our 2H-[2,7]Naphthyridin-1-One Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications including assay, impurity profile, and residual solvent analysis. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.