Description

5-Bromo-2-Bromomethylbenzoic Acid Ethyl Ester is a high-purity brominated aromatic ester serving as a versatile and critical building block in advanced organic synthesis. Its value lies in providing a reactive benzylic bromomethyl handle and an ester-protected carboxylic acid group, enabling precise molecular construction for complex targets. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in the synthesis of brominated analogs and complex heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, herbicides, and fungicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized monomers for advanced polymers and organic electronic materials.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to its reactive bromomethyl group for bioconjugation.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	5-Bromo-2-Bromomethylbenzoic Acid Ethyl Ester
CAS No.	950741-84-1
Molecular Formula	C10H10Br2O2
Molecular Weight	322.00 g/mol
Synonyms	Ethyl 5-Bromo-2-(bromomethyl)benzoate; 2-Bromomethyl-5-bromobenzoic Acid Ethyl Ester; Benzoic acid, 5-bromo-2-(bromomethyl)-, ethyl ester; Ethyl 2-(bromomethyl)-5-bromobenzoate; 950741-84-1; 5-Bromo-2-bromomethyl-benzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Bromomethylbenzoic Acid Ethyl Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are supported by comprehensive Certificates of Analysis (COA) detailing specifications and results from advanced techniques like HPLC, GC, NMR, and IR spectroscopy. We are committed to meeting the stringent requirements of cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.