Description

Quinazoline, 4-Chloro-2-(1,1-Dimethylethyl)-6-Iodo- is a high-value, multi-substituted quinazoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated structure, featuring both chlorine and iodine substituents, makes it a versatile building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with novel modes of action.
• Material Science: Used in the creation of organic semiconductors, liquid crystals, and advanced polymers due to its rigid, aromatic core.
• Chemical Biology: Serves as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies and bio-conjugation.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and catalysis research at universities and CROs.

Basic Information

Product Name	Quinazoline, 4-Chloro-2-(1,1-Dimethylethyl)-6-Iodo-
CAS No.	950576-97-3
Molecular Formula	C12H14ClIN2
Molecular Weight	348.61 g/mol
Synonyms	4-Chloro-2-tert-butyl-6-iodoquinazoline; 2-tert-Butyl-4-chloro-6-iodoquinazoline; 6-Iodo-4-chloro-2-(1,1-dimethylethyl)quinazoline; 4-Chloro-6-iodo-2-(tert-butyl)quinazoline; Quinazoline, 4-chloro-2-(1,1-dimethylethyl)-6-iodo-; 950576-97-3; tert-Butyl 4-chloro-6-iodoquinazoline-2-carboxylate (precursor related); 4-Chloro-2-(tert-butyl)-6-iodoquinazoline
EINECS	Contact for details

Quality Control

Our Quinazoline, 4-Chloro-2-(1,1-Dimethylethyl)-6-Iodo- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.