Description

8-Bromo-2-Methylquinolin-4(1H)-One is a high-purity brominated quinolinone derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core structure.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials due to its fused aromatic system.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for introducing functionalized quinoline motifs.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and discovery chemistry.

Basic Information

Product Name	8-Bromo-2-Methylquinolin-4(1H)-One
CAS No.	949507-56-6
Molecular Formula	C₁₀H₈BrNO
Molecular Weight	238.08 g/mol
Synonyms	8-Bromo-2-methyl-1,4-dihydroquinolin-4-one; 8-Bromo-2-methyl-4-quinolinol; 8-Bromo-2-methyl-4(1H)-quinolinone; 4-Hydroxy-8-bromo-2-methylquinoline; 8-Bromo-2-methyl-4-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-Methylquinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.