Description

4-Hydroxy-6-(Trifluoromethyl)Quinoline is a high-value, fluorinated quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, combining a quinoline core with a trifluoromethyl group, provides exceptional electronic properties and metabolic stability, making it indispensable for developing novel active compounds. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental persistence.
• Material Science Research: Serves as a precursor for creating organic light-emitting diodes (OLEDs) and other advanced electronic materials due to its electron-deficient quinoline structure.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel chelating ligands for catalytic processes.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on incorporating fluorine atoms into complex molecules.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical products.

Basic Information

Product Name	4-Hydroxy-6-(Trifluoromethyl)Quinoline
CAS No.	949507-45-3
Molecular Formula	C₁₀H₆F₃NO
Molecular Weight	213.16 g/mol
Synonyms	6-(Trifluoromethyl)quinolin-4-ol; 4-Hydroxy-6-trifluoromethylquinoline; 4-Quinolinol, 6-(trifluoromethyl)-; 6-Trifluoromethyl-4-hydroxyquinoline; 4-Hydroxy-6-(trifluoromethyl)chinolin; 6-Trifluoromethylquinolin-4-ol; 4-OH-6-CF3-Quinoline
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxy-6-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.