Description

8-Bromo-1H-quinolin-4-one is a versatile brominated quinolinone derivative, a key heterocyclic building block prized for its unique reactivity. This compound is essential for researchers and manufacturers developing advanced materials and active pharmaceutical ingredients (APIs). It is primarily utilized in organic synthesis, pharmaceutical R&D, and as a precursor for functionalized quinoline-based compounds.

Application

• Pharmaceutical Intermediate: A crucial synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and anticancer agent discovery.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and functional group transformations to create complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the synthesis of new compounds with potential herbicidal or pesticidal activity.
• Material Science: Employed in the development of organic electronic materials, ligands for metal complexes, and advanced polymers.
• Chemical Biology Probe: Useful for designing molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	8-Bromo-1H-quinolin-4-one
CAS No.	949507-29-3
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	8-Bromoquinolin-4(1H)-one; 8-Bromo-4-hydroxyquinoline; 8-Bromo-4-quinolinol; 8-Bromo-4(1H)-quinolinone; 4-Hydroxy-8-bromoquinoline; 8-Bromo-1,4-dihydroquinolin-4-one; 8-Bromo-4-quinolone
EINECS	Contact for details

Quality Control

Our 8-Bromo-1H-quinolin-4-one is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support R&D and commercial projects with reliable, high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.