Description

Phenol, 2-Chloro-4-Ethynyl- is a specialized halogenated phenol derivative featuring a reactive ethynyl group. This unique molecular structure makes it a valuable key intermediate in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting specific receptors or requiring complex carbon frameworks.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where the phenol and ethynyl moieties offer unique biological activity.
• Material Science Research: Acts as a monomer or precursor in the development of specialty polymers, resins, and advanced organic materials with tailored properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Sonogashira) and click chemistry applications due to its reactive ethynyl group, facilitating the creation of complex organic molecules.
• Ligand and Catalyst Development: Utilized as a precursor for synthesizing specialized ligands used in catalytic systems for asymmetric synthesis and other chemical transformations.

Basic Information

Product Name	Phenol, 2-Chloro-4-Ethynyl-
CAS No.	949114-22-1
Molecular Formula	C8H5ClO
Molecular Weight	152.58 g/mol
Synonyms	2-Chloro-4-ethynylphenol; 4-Ethynyl-2-chlorophenol; 2-Chloro-4-ethynyl-phenol; 1-Chloro-2-hydroxy-5-ethynylbenzene; Phenol, 2-chloro-4-ethynyl-; (2-Chloro-4-hydroxyphenyl)acetylene
EINECS	Contact for details

Quality Control

Our Phenol, 2-Chloro-4-Ethynyl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.