Description

5-Chloro-8-Hydroxyquinoline is a versatile halogenated hydroxyquinoline derivative, serving as a crucial synthetic intermediate and active pharmaceutical ingredient (API) in various high-value industries. Its unique molecular structure, featuring both a chloro substituent and a hydroxyl group on the quinoline backbone, imparts significant chelating and antimicrobial properties. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop advanced formulations and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of antimicrobial and antifungal agents, leveraging its inherent bioactive quinoline core.
• Agrochemical Synthesis: Used in the production of fungicides and pesticides, where its halogenated structure contributes to product efficacy.
• Metal Chelation & Corrosion Inhibition: Acts as a chelating agent in industrial processes and as an additive in metal treatment formulations to prevent corrosion.
• Research & Development: Valuable building block in organic chemistry research for creating novel heterocyclic compounds and studying coordination chemistry.
• Dye & Pigment Intermediate: Serves as a starting material for the synthesis of certain complex dyes and organic pigments.
• Analytical Reagent: Employed in analytical chemistry as a reagent for the detection and quantification of specific metal ions.

Basic Information

Product Name	5-Chloro-8-Hydroxyquinoline
CAS No.	130-16-5
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	8-Hydroxy-5-chloroquinoline; 5-Chloro-8-quinolinol; 5-Chloro-8-hydroxyquinoline; Clioquinol (API name); Iodochlorhydroxyquin (related compound); 5-Chlorooxine; Chinoform; Quinolor; 5-Cl-8-HQ
EINECS	204-984-4

Quality Control

Our 5-Chloro-8-Hydroxyquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting standards for use in pharmaceutical and fine chemical synthesis. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	122 - 126 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.