Description

3-Bromo-4-Chlorobenzonitrile is a versatile halogenated benzonitrile derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3-Bromo-4-Chlorobenzonitrile
CAS No.	948549-53-9
Molecular Formula	C7H3BrClN
Molecular Weight	216.46 g/mol
Synonyms	4-Chloro-3-bromobenzonitrile; 3-Bromo-4-chlorobenzene carbonitrile; Benzonitrile, 3-bromo-4-chloro-; 3-Bromo-4-chloro-benzonitrile; 948549-53-9; 4-Chloro-3-bromobenzonitrile; 3-Bromo-4-chlorobenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chlorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliable supply for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.