Description

5-Chloro-8-Methylquinoline-2,3-Dicarboxylic Acid Diethyl Ester is a high-purity, functionalized quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its versatile molecular scaffold, which is essential for constructing complex heterocyclic compounds with tailored properties. This product is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for anti-malarial, anti-bacterial, and kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its bioactive quinoline core.
• Material Science Research: Serves as a precursor for creating functional organic materials, including ligands for metal-organic frameworks (MOFs) and organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent probes or molecular tags for biological imaging and diagnostic applications.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel chiral or non-chiral ligands used in asymmetric catalysis and transition metal complexes.
• Academic & Contract Research: An essential reagent for methodological development in organic synthesis and medicinal chemistry within academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	5-Chloro-8-Methylquinoline-2,3-Dicarboxylic Acid Diethyl Ester
CAS No.	948294-21-1
Molecular Formula	C₁₇H₁₈ClNO₄
Molecular Weight	335.78 g/mol
Synonyms	Diethyl 5-Chloro-8-methylquinoline-2,3-dicarboxylate; 5-Chloro-8-methylquinoline-2,3-dicarboxylic acid diethyl ester; 2,3-Quinolinedicarboxylic acid, 5-chloro-8-methyl-, diethyl ester; Ethyl 5-chloro-8-methyl-2,3-quinolinedicarboxylate; 948294-21-1; 5-Chloro-8-methyl-2,3-quinolinedicarboxylic acid diethyl ester
EINECS	Contact for details

Quality Control

Our 5-Chloro-8-Methylquinoline-2,3-Dicarboxylic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.