Description

5-Bromo-2-Chloro-6-Methoxyquinoline-3-Carbonitrile is a high-value, multi-functional quinoline derivative that serves as a critical synthetic intermediate. Its unique halogenated and nitrile-substituted structure makes it an essential building block for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its reactive halogen and nitrile functional groups.
• Material Science: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Versatile scaffold for further functionalization via cross-coupling reactions, nucleophilic substitutions, and cyano-group transformations.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	5-Bromo-2-Chloro-6-Methoxyquinoline-3-Carbonitrile
CAS No.	948294-04-0
Molecular Formula	C₁₁H₆BrClN₂O
Molecular Weight	297.53 g/mol
Synonyms	5-Bromo-2-chloro-6-methoxyquinoline-3-carbonitrile; 3-Cyano-5-bromo-2-chloro-6-methoxyquinoline; 2-Chloro-5-bromo-6-methoxyquinoline-3-carbonitrile; Quinoline-3-carbonitrile, 5-bromo-2-chloro-6-methoxy-; 948294-04-0; 5-Br-2-Cl-6-MeO-quinoline-3-CN
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-6-Methoxyquinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is light-sensitive; store away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.