Description

4-Amino-7-Fluoro-2-Methylquinoline is a high-purity, functionalized quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines an amino group for nucleophilic reactivity with a fluorine atom for tuning electronic properties and metabolic stability. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and environmental persistence.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers, dyes, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile scaffold for constructing more complex heterocyclic compounds through further functionalization of the amino group or the quinoline core.
• Ligand & Catalyst Development: Utilized in the design of novel ligands for metal catalysis and in organocatalysis due to its nitrogen-containing structure.

Basic Information

Product Name	4-Amino-7-Fluoro-2-Methylquinoline
CAS No.	948293-45-6
Molecular Formula	C₁₀H₉FN₂
Molecular Weight	176.19 g/mol
Synonyms	7-Fluoro-2-methylquinolin-4-amine; 2-Methyl-7-fluoroquinolin-4-amine; 4-Amino-7-fluoro-2-methylquinoline; 7-Fluoro-2-methyl-4-quinolinamine; 4-Quinolinamine, 7-fluoro-2-methyl-; 948293-45-6; 4-Amino-7-fluoro-2-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-7-Fluoro-2-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.